A new study shows that you can get big benefits from a single minute of intense exercise. Testing out-of-shape men on stationary bicycles, one group did 45 minutes of cycling at a moderate pace (multiple sessions over three weeks), while the other group sprinted all-out in three, 20-second bursts. The surprising finding: both groups had identical gains. Endurance improved 20 percent, and insulin resistance, energy production and oxygen consumption in the muscles all jumped the same amount.